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Imiplasm-B because it is formulated based on Imidocarb Dipropionate, is indicated for the treatment and control of babesiosis, anaplasmosis and piroplasmosis as a single etiology or mixed disease in cattle. Imidocarb dipropionate is found in the formulation of IMIPLASM-B®, which is an anti-haematozoon belonging to the group of diaminidines. This substance controls the babesias and anaplasmas found in the blood, reducing their number; by not completely eradicating them, it allows the parasitized animal to develop a solid immunity against this pathological entity. Moreover, imidocarb maintains a preventive effect against the disease up to 1 month after treatment. IMIPLASM-B® has the following mechanism of action: It inhibits the energy metabolism and the synthesis of DNA of the parasite. In the first case, it blocks the aerobic metabolism of glucose, in the second, it inhibits DNA synthesis, and this is observed in the nucleus of the cells and the kinetoplast of the parasite; Upon closer observation, it is concluded that the activity of IMIPLASM-B® breaks down the mitochondrial activity of babesia, leading to its death. In addition, IMIPLASM-B® modifies the size of the nucleus and vacuolizes the cytoplasm of the parasite cells. With the aforementioned therapeutic activity, IMIPLASM-B® paralyzes the parasite in a few hours; this allows the animal’s organic defense systems to act on the babesia very quickly. IMIPLASM-B® is metabolized and eliminated slowly, it is found for long periods in plasma and tissues, it is gradually excreted. It is concentrated in the kidneys, where it is reabsorbed in its form, to be later metabolized in the liver and eliminated through urine and feces. IMIPLASM-B® is less toxic and more effective than aromatic diamidines and carbanilides. IMIPLASM-B® is enriched with cyanocobalamin (vitamin B12), which is essential for the synthesis of hemoglobin; Remember that blood cells destroy many red blood cells, which can lead to anemia, jaundice, and hemoglobinuria (blood in the urine); This vitamin helps in cell development and keeps the nervous system in good functional condition. The combination of imidocarb dipropionate and cyanocobalamin present in IMIPLASM-B® aid in the rapid recovery of treated animals.
DOSE:
For the treatment and control of Babesiosis or Anaplasmosis or mixed disease, apply at a rate of 2.5 ml per 100 kg of body weight. For the treatment and control of piroplasmosis, apply at a rate of 1 ml per 100 kg of body weight.
ROUTE OF ADMINISTRATION:
Subcutaneous or deep intramuscular.
WARNINGS:
Animals treated with this product should not be slaughtered until 20 days after the last application. Do not administer to cattle that are in dairy production. This product is exclusively for veterinary use. Veterinary use. Keep out of reach of children. Keep in a cool, dry place, away from sunlight. Keep at temperatures between 15 ° and 30 ° C. Your purchase requires a medical prescription. Consult the Veterinarian.
FORMULA:
Each mL contains:
Imidocarb Dipropionate 120 mg
Cyanocobalamin 4 mg
Vehicle, c.b.p. 1 mL.
PRESENTATIONS
50 mL bottle
100 mL bottle
Distributed for Mexico
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